Aberrant working memory processing in major depression: evidence from multivoxel pattern classification

Aberrant brain activation during a working memory task in psychotic major depression.

OBJECTIVE The authors sought to better understand the neural circuitry associated with working memory deficits in psychotic major depression by examining brain function during an N-back task. METHOD Study subjects were 16 patients with psychotic major depression, 15 patients with nonpsychotic major depression, and 19 healthy comparison subjects. Functional MRI data were collected while partic...

The Effect of Memory and Attention Adaptation Training on Working Memory and Processing Speed in Children Survived from Cancer

The aim of this study was to promote working memory and processing speed in adolescents surviving acute lymphoblastic leukemia with a history of chemotherapy, utilizing a cognitive behavior therapy (MAAT). The study population of this research included 60 adolescents survived from acute lymphoblastic leukemia with chemotherapy history attending Imam Reza outpatient oncology clinic. The partici...

Age-related differences in the neural basis of the subjective vividness of memories: evidence from multivoxel pattern classification.

Although older adults often show reduced episodic memory accuracy, their ratings of the subjective vividness of their memories often equal or even exceed those of young adults. Such findings suggest that young and older adults may differentially access and/or weight different kinds of information in making vividness judgments. We examined this idea using multivoxel pattern classification of fMR...

A processing approach to the working memory/long-term memory distinction: evidence from the levels-of-processing span task.

Recent theories suggest that performance on working memory (WM) tasks involves retrieval from long-term memory (LTM). To examine whether WM and LTM tests have common principles, Craik and Tulving's (1975) levels-of-processing paradigm, which is known to affect LTM, was administered as a WM task: Participants made uppercase, rhyme, or category-membership judgments about words, and immediate reca...

Interactions between Memory and New Learning: Insights from fMRI Multivoxel Pattern Analysis